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HtpG and SAXS PDB codes
| PDB code | revision | reference | resolution | description | download PDB |
| Krukenberg, et al, 2009 | Grp94 Extended SAXS Model | Grp94 | |||
| Hsc82 Extended SAXS Model | Hsc82 | ||||
| Hsp90 Extended SAXS Model | Hsp90 | ||||
| HtpG High pH SAXS Model | HtpG-Hi | ||||
| HtpG Low pH SAXS Model | HtpG-Lo | ||||
| 2GQ0 | Shiau, et al, 2006 | 1.9Å | Crystal Structure of the Middle Domain of HtpG, the E. coli Hsp90 | 2GQ0 | |
| 2IOR | 1.65Å | Crystal Structure of the N-terminal Domain of HtpG, the Escherichia coli Hsp90, Bound to ADP | 2IOR | ||
| 2IOQ | 3.5Å | Crystal Structure of Full-length HtpG, Escherichia coli Hsp90 | 2IOQ | ||
| 2IOP | 3.55Å | Crystal Structure of Full-length HtpG, the Escherichia coli Hsp90, Bound to ADP | 2IOP | ||
| Structure of the extended dimer of HtpG, the Escherichia coli Hsp90, Bound to ADP | ADP-EXT | ||||
| Structure of the proposed compact dimer of HtpG, the Escheria coli Hsp90, Bound to ADP | ADP-CLOSED | ||||
| 1SF8 | 19 Feb 2004 | Harris, et al, 2004 | 2.60Å | Crystal structure of the carboxy-terminal domain of htpG, the E. coli Hsp90 | 1SF8 |
References
Krukenberg KA, Southworth DR, Street TO, Agard DA, "pH-Dependent Conformational Changes in Bacterial Hsp90 Reveal a Grp94-Like Conformation at pH 6 That Is Highly Active in Suppression of Citrate Synthase Aggregation," J Mol Biol. 2009 May 7. (html, pdf)
Shiau AK, Harris SF, Southworth DR, Agard DA, "Structural Analysis of E. coli hsp90 Reveals Dramatic Nucleotide-Dependent Conformational Rearrangements," Cell. 2006 Oct 20;127(2):329-340 (html or pdf).
Seth F. Harris, Andrew K. Shiau and David A. Agard, "The Crystal Structure of the Carboxy-Terminal Dimerization Domain of htpG, the Escherichia coli Hsp90, Reveals a Potential Substrate Binding Site," Structure, (2004) 12(6):1087-1097 (pdf).
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