Daniel Southworth

post doctorate

Room S416
Department of Biochemistry & Biophysics
University of California, San Francisco
Mission Bay, Genentech Hall
600 16th St
San Francisco CA
94158-2517
(415) 502-2930 (Ph)
(415) 476-1902 (Fax)

Publications

Shiau AK, Harris SF, Southworth DR, Agard DA, "Structural Analysis of E. coli hsp90 Reveals Dramatic Nucleotide-Dependent Conformational Rearrangements," Cell. 2006 Oct 20;127(2):329-340(html or pdf).

Sharma D, Southworth DR, Green R, "EF-G-independent reactivity of a pre-translocation-state ribosome complex with the aminoacyl tRNA substrate puromycin supports an intermediate (hybrid) state of tRNA binding." RNA. 2004 Jan;10(1):102-13. (pdf)

Maki JA, Southworth DR, Culver GM, "Demonstration of the role of the DnaK chaperone system in assembly of 30S ribosomal subunits using a purified in vitro system." RNA. 2003 Dec;9(12):1418-21. (pdf)

Cukras AR, Southworth DR, Brunelle JL, Culver GM, Green R, "Ribosomal proteins S12 and S13 function as control elements for translocation of the mRNA:tRNA complex." Mol Cell. 2003 Aug;12(2):321-8. (pdf)

Southworth DR, Green R, "Ribosomal translocation: sparsomycin pushes the button." Curr Biol. 2003 Aug 19;13(16):R652-4. (pdf)

Southworth DR, Brunelle JL, Green R, "EFG-independent translocation of the mRNA:tRNA complex is promoted by modification of the ribosome with thiol-specific reagents." J Mol Biol. 2002 Dec 6;324(4):611-23.(pdf)