Macromolecular Interactions BP204A

Fall 2007 and Winter 2008 Lecture Schedule

Monday Wednesday Friday
Sept 10

No Class

Sept 12

No Class

Sept 14
Jacobsen
Protein-Ligand
Association
Notes for Sep 14-19
Sept 17
Jacobsen
Protein-Ligand
Association
Paper

Discussion Questions
Sept 19
Jacobsen
Protein-Ligand
Association
Paper

Discussion Questions
Sept 21
Stroud
Protein-Ligand
Association
Lecture notes
Paper 1 | Paper 2

Discussion Questions
Sept 24
Stroud
Protein-Ligand
Association
Lecture notes


Paper

Discussion Questions
Sept 26
Stroud
Protein-Ligand
Association
Lecture notes

Electrostatics Notes

Paper

Discussion Questions
Sept 28
No Class
BP: Tiburon retreat

Oct 1
Stroud
Crystallography

Lecture notes

Additional Notes
Oct 3
Stroud
Crystallography

Paper1| Paper 2
Supplementary Text
Supplementary Figures
Discussion Questions
Oct 5
Jacobsen
Simulating Molecular
Interactions

Notes

Paper


Discussion Questions
Oct 8
Jacobsen
Simulating Molecular
Interactions
Paper


Discussion Questions
Oct 10
Jacobsen
SImulating Molecular
Interactions
Paper


Discussion Questions
Oct 12
Agard
Mechanisms of
Protein Folding
Paper

Lecture notes
Oct 15
Agard
Mechanisms of
Protein Folding
Paper1| Paper2

Discussion Questions
Oct 17
Agard
Mechanisms of
Protein Folding
Oct 19
Gross
NMR
Notes
Oct 22
Gross & Agard
NMR & Protein Folding

Paper
Discussion Questions
Oct 24
Agard
CD & Fluorescence
Oct 26
Agard
CD & Fluorescence
Paper
Discussion Questions
Oct 29
Agard
CD & Fluorescence
Paper1 | Paper2
Discussion Questions
Oct 31
Agard
CD & Fluorescence
Paper
Nov 2
Miller
Catalysis Practicals
Notes
Nov 5
Miller
TST, TS binding
and inhibition
Paper 1 | Paper 2 | Paper 3
Discussion Questions
Notes
Nov 7
Miller
GS effects
Paper 1 | Paper 2
Discussion Questions
Notes
Nov 9
Miller
Allosteric regulation
Paper 1 | Paper 2 | Paper 3
Discussion Questions
Notes
Nov 12
Miller
H-tunneling
Paper1 | Paper2
Notes
Nov 14
Miller & Gross
NMR & dynamics
Paper
Discussion Questions
Nov 15 (Thursday!)
Miller & Gross
Conformational change
and catalysis
Paper
Discussion Questions
Nov 19
Miller & Gross
Loops & catalysis
Paper
Nov 21
Jacobsen
Single Molecular
Events
Paper1 | Paper2
Discussion(4) | Discussion(5)
End of Fall Quarter
Proposals due Nov 26
Dec 31
No Class
Jan 2
No Class

Jan 4
Fletterick
Protein-Protein Interactions

Notes
Jan 7
Fletterick
Protein Protein Interactions
Discussion Questions
Jan 9
Fletterick
Protein Protein Interactions
Notes
Discussion Questions
Jan 11
Fletterick
Protein Protein Interactions
Notes
Discussion Questions
Jan 14
Fletterick
Protein Protein Interactions
Discussion Questions
Lecture Notes
Jan 16
Fletterick
Protein Protein Interactions
Discussion Qestions
Lecture Notes
Jan 18
Minor
ITC & Analytical
Ultracentrifugation
Lecture Notes
No Discussion Today
Jan 21
No Class
Martin Luther King, Jr Day
Jan 23
Frankel
Protein Nucleic Acid
Interactions
Lecture Notes
No Discussion
Jan 25
Frankel
Protein Nucleic Acid
Interactions
Lecture Notes
Discussion Questions
Paper
Jan 28
Frankel
Protein Nucleic Acid
Interactions
Lecture Notes
Discussion Questions
Paper
Jan 30
Frankel
Protein Nucleic Acid
Interactions
Lecture Notes
No Discussion
Feb 1
Frankel
Preproposal Due in Class
Protein Nucleic Acid
Interactions
Lecture Notes
Discussion Questions
Paper
Feb 4
No Lecture
Proposal Discussion
Feb 6
Minor
Membrane Channels
Lecture Notes
No Discussion
Feb 8
Minor
Membrane Channels
Discussion Questions
Feb 11
Minor
Membrane Channels
Discussion Questions
Feb 13
Cheng
Electron Microscopy
Lecture Notes
No Discussion
Feb 15
Cheng
Electron Microscopy
Lecture Notes
Discussion Questions
Paper
Feb 18
No Class
Presidents Day
Feb 20
Cheng
Electron Microscopy
Lecture Notes
No Discussion
Feb 22
Cheng
Electron Microscopy
Lecture Notes
Discussion Questions
Paper 1
Paper 2
First Draft of Proposal
Due in Class
Feb 25
Cheng
Electron Microscopy
Lecture Notes
Discussion Questions
Paper 1
Paper 2
Feb 27
Krutchinsky
Mass Spectrometry
Lecture Notes
Group Discussion
Paper 1
Paper 2
Feb 29
Krutchinsky
Mass Spectrometry
Lecture cont. from Feb 27
No Discussion

Mass Spec Demo in
S132
Mar 3
Krutchinsky
Mass Spectrometry
Paper 1
Paper 2
Mar 5
No Class
Mar 7
No Class
Mar 10
No Class
Mar 12
No Class
Mar 14
No Class
Written Proposals due at Noon

Mar 17
Oral Defenses

Mar 19
Oral Defenses
Mar 21
Oral Defenses

Discussion Groups

Gibbs Sanger Franklin Pauling
Hannes Braberg Gabriel Rocklin Jennifer Hsiao David Burkhardt
Charlie Kehoe Noah Ollikainen David Booth Joe Kliegman
Adam Marko Monica Tremont Bethany Simmons Kiyoshi Egami
George Masologites Elaine Kirschke Brittany Belin Christopher Wen
Peter Skewes-Cox Heather Newman Jaline Gerardin

contact david.stanley@ucsf | 2007