Macromolecular Interactions BP204A

Background Reading


Proteins - Structures and Molecular Properties
by Creighton T.E. 2nd. Edition, published by Freeman.
Purchase at Millberry bookstore, Amazon, etc.

The most relevant material is:
Ch. 1 pgs. 1-31, Ch. 4, Ch. 5, Ch. 9
PDFs available here: Chapters: 1 4 5 9.1-2 9.3 9.4

Methods Resources

The texts listed here can be found in and borrowed from Julie's office, and may come in handy but are not required for the problem sets.

General/Multiple Topic Books
Methods in Modern Biophysics
by Bengt Nölting, Published by Springer
Topics include: Chromatography, Mass Spectrometry, X-ray Crystallography,
Infrared Spectroscopy, Electron Microscopy, Scanning Probe Microscopy,
Nanotechnology, Proteomics, Ion Mobility Spectrometry
Purchase Here

Biophysical Chemistry: Part II: Techniques for the Study of Biological Structure and Function
by Cantor and Schimmel, Published by Freeman
Great, classic text.  Heavy on math and physics in explantations.
Purchase Here


Crystallography
Crystallography Made Crystal Clear
by Gale Rhodes, Published by Academic Press
A great overview text on crystallography.
Puchase Here 

PyMol

We'll be using the PyMol package to visualize and study biological macromolecules and their interactions. It's a good idea to get comfortable with the basic functions by exploring some structures from the Protein Data Bank and browsing the PyMol help pages.

Some useful links:
contact david.stanley@ucsf | 2007