Research

Intracellular pathogens must hijack host proteins and signaling networks to evade the innate immune system and acquire nutrients. My research investigates the interaction between the C. trachomatiseffector protein IncE and mammalian sorting nexins.

Publications

Xue C, Whitis NR, Sashital DG. Conformational Control of Cascade Interference and Priming Activities in CRISPR Immunity. Mol Cell. 2016 Nov 17;64(4):826-834. doi: 10.1016/j.molcel.2016.09.033. Epub 2016 Oct 27. PMID: 27871367; PMCID: PMC5561731.