UCSF Macromolecular Structure Group

Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data.

Siyuan Du, Stephanie A. Wankowicz, Filip Yabukarski, Tzanko Doukov, Daniel Herschlag, James S. Fraser

A large inner membrane pore defines the ESX translocon.

Hedgehog pathway activation through conformational blockade of the Patched sterol conduit.

Accelerating Protein Design Using Autoregressive Generative Models.

The structure of a calsequestrin filament reveals mechanisms of familial arrhythmia.

Modulating pathogenesis with Mobile-CRISPRi.

Synthetic Development: Learning to Program Multicellular Self-Organization.

Two accessory proteins govern MmpL3 mycolic acid transport in mycobacteria.

DNA-scaffolded biomaterials enable modular and tunable control of cell-based cancer immunotherapies.

IMMU-57. SEQUENTIAL TWO-RECEPTOR PRIMING CAR SYSTEM TO OVERCOME HETEROGENEOUS ANTIGEN EXPRESSION.

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