eLife

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.

eLife

Miller-Vedam LE, Bräuning B, Popova KD, Schirle Oakdale NT, Bonnar JL, Prabu JR, Boydston EA, Sevillano N, Shurtleff MJ, Stroud RM, Craik CS, Schulman BA, Frost A, Weissman JS

Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells.

eLife

Stoeber M, Jullié D, Li J, Chakraborty S, Majumdar S, Lambert NA, Manglik A, von Zastrow M

Defective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation in Neisseria meningitidis.

eLife

Williams AH, Wheeler R, Deghmane AE, Santecchia I, Schaub RE, Hicham S, Moya Nilges M, Malosse C, Chamot-Rooke J, Haouz A, Dillard JP, Robins WP, Taha MK, Gomperts Boneca I

The structure of the endogenous ESX-3 secretion system.

eLife

Poweleit N, Czudnochowski N, Nakagawa R, Trinidad D, Murphy KC, Sassetti CM, Rosenberg OS

The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins.

eLife

Ngo AM, Shurtleff MJ, Popova KD, Kulsuptrakul J, Weissman JS, Puschnik AS

Ceapins block the unfolded protein response sensor ATF6a by inducing a neomorphic inter-organelle tether.

eLife

Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P

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