eLife

Engineering ER-stress dependent non-conventional mRNA splicing.

eLife

Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P

Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor.

eLife

Livingston KE, Mahoney JP, Manglik A, Sunahara R, Traynor JR

An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.

eLife

Keedy DA, Hill ZB, Biel JT, Kang E, Rettenmaier TJ, Brandao-Neto J, Pearce NM, von Delft F, Wells JA, Fraser JS

The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins.

eLife

Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky J, Frost A, Borner GH, Weissman JS

Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates.

eLife

Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK

Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates.

eLife

Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK

Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins.

eLife

Martinko AJ, Truillet C, Julien O, Diaz JE, Horlbeck MA, Whiteley G, Blonder J, Weissman JS, Bandyopadhyay S, Evans MJ, Wells JA

Targeting RAS driven human cancer cells with antibodies to upregulated and essential cell-surface proteins.

eLife

Martinko AJ, Truillet C, Julien O, Diaz J, Horlbeck MA, Whiteley G, Blonder J, Weissman JS, Bandyopadhyay S, Evans M, Wells JA

The Human Cell Atlas.

eLife

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N

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